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The fourth generation of medical education, which has emerged alongside the new technological revolution, has led to changes in the paradigm and philosophy of medical education. This article reviews the development process of the three generations of medical education reforms, analyzes the connotation of the fourth generation of medical education reform, and highlights its characteristics centered on health, as well as its cross-disciplinary, integrated, and artificial intelligence-enabled nature. It suggests that in the face of the fourth generation of medical education reform, medical education practitioners should actively respond to changes by reconstructing the mechanisms and models of medical education, adjusting the curriculum system, updating course content, and improving evaluation methods. The article recommends that professionals in the field of medical education actively embrace and accept the fourth generation of medical education in both philosophy and action, thereby establishing a new paradigm of medical education in the context of the new technological revolution and cultivating high-quality talents capable of fulfilling the Healthy China strategy.